Serum Neurofilament

Light Chain Reference App

Please provide a valid email address to receive an access code for the application

Serum Neurofilament Light Chain Reference App

Levels of serum neurofilament light chain (sNfL) increase with age and decrease with body mass index (BMI). The application can be used to calculate age- and BMI-adjusted sNfL percentile values and Z-scores.

These two interchangeable measures quantify the deviation of the entered sNfL value in comparison to control persons of the same age and BMI, based on a reference database of 4532 persons. (Benkert et al., Lancet Neurology 2022; 21: 244–55.)

How to get access?

Please provide your email address to receive an access token. The application will prompt for additional registration for more extensive evaluations.

Measurement of sNfL

Clinicians are welcome to send patients' serum samples to the Multiple Sclerosis Centre at the University Hospital Basel in Switzerland for measurement of NfL levels. Details are available in the order form below:

Measurement Order Form (PDF, DE, 86KB)

Adjust your values and define output

Provide age, NfL levels and body mass index to automatically receive adjusted percentiles and Z-scores

Immediate results

Get an immediate visual representation of your data with respect to values in the NfL reference database

Adjust Your Values And Define Output

Provide the age, NfL levels and optionally body mass index and the app calculates adjusted percentiles and Z-scores.

Immediate results

Get an immediate visual representation of your data with respect to values in the NfL reference database.