Serum Neurofilament

Light Chain Reference App (Paediatric)

Please provide a valid email address to receive an access code for the application

Serum Neurofilament Light Chain Reference App

This is the serum neurofilament light chain (sNfL) reference app for measurements in children and adolescents. For measurements in adults please go to: shiny.dkfbasel.ch/baselnflreference.

NfL levels in children are strongly associated with age. The application can be used to calculate age-adjusted sNfL percentile values and Z score.

These two interchangeable measures quantify the deviation of the entered sNfL value in comparison to control persons of the same age, based on a reference database of 2667 healthy children and adolescents. (Abdelhak et al., Lancet Neurology 2023)

How to get access?

Please provide your email address to receive an access token. The application will prompt for additional registration for more extensive evaluations.

Measurement of sNfL

Clinicians are welcome to send patients' serum samples to the Multiple Sclerosis Centre at the University Hospital Basel in Switzerland for measurement of NfL levels. Details are available in the order form below:

Measurement Order Form (PDF, DE, 86KB)

Adjust your values and define output

Provide age and NfL levels to automatically receive adjusted percentiles and Z score

Immediate results

Get an immediate visual representation of your data with respect to values in the NfL reference database

Adjust Your Values And Define Output

Provide the age, NfL levels and optionally body mass index and the app calculates adjusted percentiles and Z score.

Immediate results

Get an immediate visual representation of your data with respect to values in the NfL reference database.