This is the serum neurofilament light chain (sNfL) reference app for measurements in children and adolescents. For measurements in adults please go to: shiny.dkfbasel.ch/baselnflreference.
NfL levels in children are strongly associated with age. The application can be used to calculate age-adjusted sNfL percentile values and Z score.
These two interchangeable measures quantify the deviation of the entered sNfL value in comparison to control persons of the same age, based on a reference database of 2667 healthy children and adolescents. (Abdelhak et al., Lancet Neurology 2023)
Please provide your email address to receive an access token. The application will prompt for additional registration for more extensive evaluations.
Clinicians are welcome to send patients' serum samples to the Multiple Sclerosis Centre at the University Hospital Basel in Switzerland for measurement of NfL levels. Details are available in the order form below: